Pseudohemophilia
Von Willebrand’s Disease (Pseudohemophilia): Von Willebrand’s disease occurs as commonly as true hemophilia. The increasing recognition is related to more reliable factor VIII assays. This hereditary disorder of hemostasis is transmitted as an autosomally dominant trait and, accordingly, appears in consecutive generations with males and females equally affected. The disease is characterized by a diminution of the level of factor VIII activity. The reduction of factor VIII activity usually is not as great as that seen in classical hemophilia. Also unlike classical hemophilia, where factor VIII activity remains constant, in the patient with von Willebrand’s disease variation in the level of circulating factor VIII activity may be noted.
Author Dr Santosh Guptha Associated withMedical Coding Billing Training
